Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.10b
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- Pages.137-137
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- 2003
Ddt Increase Aromatase Gene Expression and Activity in Leydig Cells
- Lee, Kyung-Jin (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University) ;
-
Kim, Ji-Young
(Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University)
;
- Shin, Dong-Weon (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University) ;
- Cho, Young-Rhan (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University) ;
- Jung, Kyung-Sik (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University) ;
-
You, Ho-Jin
(Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University)
;
- Jeong, Hye-Gwang (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University)
- Published : 2003.10.01
Abstract
Dichlorodiphenyltrichloroethane (DDT) is a widespread environmental pollutant. Earlier reports have demonstrated that DDT is an endocrine-active compound capable of affecting early-stage sexual differentiation in male rats. Experiments based on receptor binding affinity and receptor-mediated transcriptional activation have identified DDE as an androgen receptor antagonist.(omitted)