Effect of B-Ring-Oh Numbers of 5,7-Dihydroxyflavone on the Activity of Cyp1 Enzymes

  • Lee, Sang-Bum (School of Lifesciences and Biotechology, Korea University) ;
  • Kim, Hyun-Jung (School of Lifesciences and Biotechology, Korea University) ;
  • Kim, Hwan-Mook (Korea Research Institute of Bioscience and Biotechnology) ;
  • Park, Young-In (School of Lifesciences and Biotechology, Korea University) ;
  • Dong, Mi-Sook (School of Lifesciences and Biotechology, Korea University)
  • Published : 2003.10.01

Abstract

CYP1 enzymes, CYP1A1, CYP1A2 and CYP1B1, are known to bioactivate procarcinogens particularly polyaromatic compounds. Flavonoids are a class of natural compounds that are present in edible plants. Structurally, these compounds are polyphenols with two aromatic rings (A, B) and a heterocycyclic ring (C).(omitted)

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