대한약학회:학술대회논문집 (Proceedings of the PSK Conference)

대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

Quercetin 3-O-$\alpha$-arabinofuranoside protects heart-derived H9c2 cells against oxidative injury through maintaining MMP

  • Kim, Mi-Young (Dept. of Physiology, School of Medicine, Ajou Univ.) ;
  • Jung, Yi-Sook (Dept. of Physiology, School of Medicine, Ajou Univ) ;
  • Kim, Young-Ho (Coll. of Pharmacy, Chung Nam natl. Univ) ;
  • Baik, Eun-Joo (Dept. of Physiology, School of Medicine, Ajou Univ) ;
  • Lee, Soo-Hwan (Dept. of Physiology, School of Medicine, Ajou Univ) ;
  • Moon, Chang-Hyun (Dept. of Physiology, School of Medicine, Ajou Univ.)
  • 발행 : 2003.04.01
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초록

In this study. we investigated whether the cardioprotective effect shown by quercetin 3-O-$\alpha$-arabinofuranoside extracted from Lindera erythrocarpa against ROS-induced cell death in H9c2 cardiac myocytes. Cell death was induced by BSO, buthionine sulfoximine, which inhibits GSH level and subsequntly increase ROS level. Cell death was quntitatively determined by measuring lactate dehydrogenase (LDH) activity. (omitted)

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