The Joins (SKI 306X) study: Effects on gastric mucosa and the diclofenac-induced gastric lesions

  • Kim, Joo-Hyon (Life Science Research Center SK Chemicals and Aju university Medical college) ;
  • Lee, Hae-In (Life Science Research Center SK Chemicals and Aju university Medical colleg) ;
  • Jung, In-Ho (Life Science Research Center SK Chemicals and Aju university Medical colleg) ;
  • Jung, Ki-Won (Life Science Research Center SK Chemicals and Aju university Medical colleg) ;
  • Han, Chang-Kyun (Life Science Research Center SK Chemicals and Aju university Medical colleg) ;
  • Kwak, Wie-Jong (Life Science Research Center SK Chemicals and Aju university Medical colleg) ;
  • Cho, Yong-Baik (Life Science Research Center SK Chemicals and Aju university Medical colleg) ;
  • Joo, Hee-Jae (Life Science Research Center SK Chemicals and Aju university Medical college)
  • Published : 2003.04.01

Abstract

Joins (SKI 306X) is now clinically used for the treatment of osteoarthritis (OA). In previous reports, Joins, a natural herbal product extracted from three herbs Clematis Radix, Trichosanthes Radix and Prunella Flos, was shown to have good analgesic and anti-inflammatory effects and cartilage protective effects in several experimental models. In this study we characterized the effects of Joins on the gastric mucosa and compared to that of diclofenac. (omitted)

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