대한약학회:학술대회논문집 (Proceedings of the PSK Conference)

대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

CKD-501 INDUCED GLUCOSE TRANSPORT WAS MAINLY CAUSED BY THE STIMULATION OF GLUCOSE TRANSPOTER- TRANSLOCATION IN L6-MYOTUBES

  • Moon, C.K. (Lab of hygienic chemistry, college of pharmacy, Seoul National University) ;
  • Jung, A.Y. (Lab of hygienic chemistry, college of pharmacy, Seoul National University) ;
  • Kim, M.H. (Lab of hygienic chemistry, college of pharmacy, Seoul National University) ;
  • Lee, Y.H. (Lab of hygienic chemistry, college of pharmacy, Seoul National University) ;
  • Chae, S.H. (Lab of hygienic chemistry, college of pharmacy, Seoul National University) ;
  • Kim, K.S. (Lab of hygienic chemistry, college of pharmacy, Seoul National University) ;
  • Jo, Y.Y. (Lab of hygienic chemistry, college of pharmacy, Seoul National University) ;
  • Kim, M.H. (Lab of hygienic chemistry, college of pharmacy, Seoul National University) ;
  • Moon, K.S. (CKD, Research Institute)
  • 발행 : 2003.04.01
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초록

A newly synthesized thiazolodinedione derivative, CKD-501, was confirmed to have antihyperglycemic effect in in vivo study. The present study was undertaken to investigate the effect of CKD-501 on glucose transport and its stimulating mechanism in L6-myotubes. L6-myoblasts were cultured and differentiated to myotubes by reducing serum concentration in media from 10％ to 2％. (omitted)

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