대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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- Pages.172.2-173
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- 2003
Naringenin Inhibits Dimethylnitrosamine-Induced Hepatic Fibrosis in Rats
- Lee, Mi-Hye (College of Pharmacy, Pusan National University) ;
- Shin, Mi-Ok (Department of Anatomy, College of Medicine, Pusan National University) ;
- Yoon, Sik (Department of Anatomy, College of Medicine, Pusan National University) ;
- Moon, Jeon-Ok (Department of Anatomy, College of Medicine, Pusan National University)
- 발행 : 2003.04.01
초록
Naringenin, a phytoalexin found in grapefruit. has been reported to exhibit a wide range of pharmacological properties. The aim of the present study is to evaluate the protective effect of naringenin on hepatic fibrosis induced by dimethylnitrosamine (DMN) in rats. Fibrosis was induced by intraperitoneal injection of DMN. Naringenin was given orally at 20 mg/kg and 50 mg/kg daily for 4 weeks. (omitted)
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