Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

The Influence of Bisphenol A on the Thyroid Hormone System in vivo

  • Cho, Mi-Young (National Institute of Toxicological Research, Biochemical Pharmacology Div., Ajou University) ;
  • Jung, Ki-Kyung (National Institute of Toxicological Research, Biochemical Pharmacology Div., Ajou University) ;
  • Nam, Kyung-Tak (National Institute of Toxicological Research, Biochemical Pharmacology Div., Ajou University) ;
  • Kang, Ju-Hye (National Institute of Toxicological Research, Biochemical Pharmacology Div., Ajou University) ;
  • Kang, Seog-Youn (National Institute of Toxicological Research, Biochemical Pharmacology Div., Ajou University) ;
  • Chung, Hye-Joo (National Institute of Toxicological Research, Biochemical Pharmacology Div., Ajou University) ;
  • Kim, Ju-Il (National Institute of Toxicological Research, Biochemical Pharmacology Div., Ajou University) ;
  • Lee, Young-Don (Ajou University, School of Medicin) ;
  • Na, Han-Kwang (National Institute of Toxicological Research, Biochemical Pharmacology Div., Ajou University)
  • Published : 2003.04.01
Download PDF
⟨ Previous Next ⟩

Abstract

It is well-known that bisphenol A(BPA), an industrial raw material for polycarbonate and epoxy resins, shows estrogenic activity. Recent research from our laboratory has shown that SPA disrupts interaction between thyroid hormone and its receptor in a non-competitive manner, and alters the thyroid-hormone dependent expression of growth hormone(GH) and prolactin(PRL). (omitted)

Keywords