대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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- Pages.189.1-189.1
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- 2003
Development and Validation of the Custom Human cDNA Microarray (KISTCHIP-400) for Monitoring Expression of Genes involved in Hormone Disruption
- Kim, Youn-Jung (Toxicology Laboratory, Korea Institute of Science ＆ Technology) ;
- Yun, Hye-Jung (Toxicology Laboratory, Korea Institute of Science ＆ Technolog) ;
- Chang, Suk-Tai (Toxicology Laboratory, Korea Institute of Science ＆ Technolog) ;
- Jeon, Hee-Kyung (Toxicology Laboratory, Korea Institute of Science ＆ Technolog) ;
- Ryu, Jae-Chun (Toxicology Laboratory, Korea Institute of Science ＆ Technology)
- 발행 : 2003.04.01
초록
Transcript profiling is a particularly valuable tool in the field of steroid receptor biology, as these receptors are ligand-activated transcription factors and therefore exert their initial effects through altering gene expression in responsive cells. Also, an increased awareness of endocrine disrupting chemicals (EDCs) and their potential to affect wildlife and humans has produced a demand for practical screening methods to identify endocrine activity. (omitted)
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