대한약학회:학술대회논문집 (Proceedings of the PSK Conference)

대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

Diarylheptanoid Isolated from Alpinia officinarum Inhibits Pancreatic Lipase

  • Shin, Ji-Eun (Department of Food Science, and College of Pharmacy, Kyung Hee University) ;
  • Song, Myoung-Chong (Department of Food Science, and College of Pharmacy, Kyung Hee University) ;
  • Han, Myung-Joo (Department of Food Science, and College of Pharmacy, Kyung Hee University) ;
  • Baek, Nam-In (Department of Food Science, and College of Pharmacy, Kyung Hee University) ;
  • Kim, Dong-Hyun (Department of Food Science, and College of Pharmacy, Kyung Hee University)
  • 발행 : 2003.04.01
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초록

Pancreatic lipase-inhibitory activity of the rhizome of Alpinia officinarum (AO) and its antihyperlipidemic activity were measured. When water extract of AO was stepwise fractionated with organic solvents, ethylacetate fraction exhibited the most potent inhibition. From it, Diarylheptanoid was isolated as an inhibitor of pancreatic lipase and we investigated its in vitro inhibitory effect of lipase activity and in vivo antihyperlipidemic effect. (omitted)

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