대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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- Pages.254.1-254.1
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- 2003
A chemical proteomic approach for in vivo evaluation of CCl4 effect on the acute serum proteins.
- Uhm, Young-Ho (Graduate School of East-West Medical Science Kyung Hee University) ;
- Kim, Young-Doo (Graduate School of East-West Medical Science Kyung Hee University) ;
- Seo, Eun-Seok (Graduate School of East-West Medical Science Kyung Hee University) ;
- Kang, Tae-Hyuk (Graduate School of East-West Medical Science Kyung Hee University) ;
- Kang, Dong-Hoon (Graduate School of East-West Medical Science Kyung Hee University) ;
- Soh, Yun-Jo (Graduate School of East-West Medical Science Kyung Hee University) ;
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Kang, Chul-Hun
(Graduate School of East-West Medical Science Kyung Hee University)
- 발행 : 2003.04.01
초록
CCl4 has been known as typical chemical which induce acute hepatitis accompanying increase in the levels of acute phase proteins in serum. In this study, after acute liver damage was induced by CCl4 in Sprague-Dawley rats, the levels of serum acute phase proteins were examined using 2-dimensional electrophoresis and lactic dehydrogenase (LDH), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels in blood were also examined at 1, 2, 3 days after the induction to confirm acute hepatitis. (omitted)
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