Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.262.1-262.1
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- 2003
A Rapid Manufacturing Process of Crude Cordycepin Containing Adenosine (CCCA) from Cultured Fruiting Bodies of Cordyceps Milifads (CM) for Developing Anti-leukemic Agents.
- Lee, Seung-Jung (C. M. Biotec) ;
- Kwon, Oh-Seung (BBRC, Korea Inst. of Sci. and Tech) ;
- Park, Eun-A (BBRC, Korea Inst. of Sci. and Tech) ;
- Ko, Sung-Kwon (Korea Ginseng Inst., Chung-Ang Univ) ;
- Kim, Ha-Won (Dept. of Life Sci.. Univ. of Seou) ;
- You, Byeong-Jin (Dept. of Food Sci., Kangnung National Univ) ;
- Lee, Jae-Hee (College of Pharmacy, Chung-Ang Univ) ;
- Lee, Min-Won (College of Pharmacy, Chung-Ang Univ.)
- Published : 2003.04.01
Abstract
Anti-tumor, anti-viral and anti-leukemic activity of cordycepin are well known. Adenosine was reported to induce an apoptosis in human leukemia cells. CM has been widely used as traditional medicinal herbs in China. Previously, we reported the results relating the isolation and characterization of cordycepin and adenosine from the cultured fruiting bodies of CM. We further studied the manufacturing process of CCCA for the prupose of developing anti-leukemic agents. (omitted)
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