대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
- /
- Pages.282.2-283
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- 2003
Chiral Separation of Non-Steroidal Inflammatory Drugs as Dual Diastereomeric Derivatives with (R)-and (S)-Phenylethylamines
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Lee, Yoon-Suk
(College of Pharmacy, Sungkyunkwan University)
;
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Paik, Man-Jeong
(College of Pharmacy, Sungkyunkwan University, Kyonggi Pharmaceutical Research Cente)
;
- Kim, Kyoung-Rae (College of Pharmacy, Sungkyunkwan University)
- 발행 : 2003.04.01
초록
The carboxylated acidic non-steroidal antiinflammatory drugs (NSAIDs) constitute the principal class of agents for controlling the pain and inflammation of the rheumatic diseases. It is mostly administered as a racemic mixture like most other drugs with asymmetric carbon atoms. However enantiomers of many racemic drug substances have been shown to posses different pharmacological toxicological properties. (omitted)
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