Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Simple and Sensitive Determination of Baclofen in Human Plasma by Column-Switching and Semi-Micro High-Performance Liquid Chromatography

  • Ban, Eun-Mi (Physical Pharmacy Laboratory, College of Pharmacy, Seoul National University) ;
  • Ko, Hye-Ran (Physical Pharmacy Laboratory, College of Pharmacy, Seoul National University) ;
  • Kim, Chong-Kook (Physical Pharmacy Laboratory, College of Pharmacy, Seoul National University)
  • Published : 2003.04.01
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Abstract

Using a column-switching technique. highly sensitive and selective semi-micro high-performance liquid chromatographic (HPLC) method has been developed for the determination of baclofen in human plasma. Following precipitation of plasma sample containing baclofen with zinc sulfate-acetonitrile, samples were directly injected on to the system. (omitted)

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