Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
- /
- Pages.299.2-300
- /
- 2003
Preparation and Evaluation of Bupivacaine-loaded Microspheres by Solvent Extraction Method
- Kim, Min-Soo (College of Pharmacy, Chungnam National University) ;
-
Hwang, Sung-Joo
(College of Pharmacy, Chungnam National University)
- Published : 2003.04.01
Abstract
Various bupivacaine-Ioaded microspheres were prepared with poly (d,l-Iactide) (PLA) by solvent extraction method. The internal solution of polymer(PLA R104) and drug in glacial acetic acid was introduced into the external phase of polyvinylpyrrolidone (PVP K-30) in polyethyleneglycol (PEG), and emulsified to be an oil-in-oil (o/o) emulsion. The o/o emulsion was poured to the buffer solution. (omitted)
Keywords