Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.97.1-97.1
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- 2003
Antidiabetic Activity of Formular containing an Euonymus alata and Mori Foluim in Multiple Low Dose Streptozotocin-induced Rats
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Chung, Sung-Hyun
(laboratory of Pharmacology, School of Pharmacy, Kyung Hee University)
;
- Lee, Sung-Hyun (Laboratory of Pharmacology, School of Pharmacy, Kyung He University) ;
- Kim, Hee-Ja (Laboratory of Pharmacology, School of Pharmacy, Kyung He University)
- Published : 2003.10.01
Abstract
Antidiabetic activity of formular containing an Euonymus alata (EA) and Mori Foluim (MF) was investigated in oral glucose tolerance test (OGTT) and multiple low dose Streptozotocin (MLDSTZ)-induced rats. Optimum ratio between EA and MF was found to be 1:1 in OGTT, and two strengths (250 and 500 mg/kg for each medicinal plant) were coadministered with 20 mg/kg of STZ in 5 consecutive days. At 3rd week, water and food intakes were compared between groups and polydipsia and polyphagia shown in diabetic control were markedly improved in dose dependent manner. (omitted)
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