Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.140.1-140.1
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- 2003
Inhibition of proliferation of human breast cancer cell (SK-BR3) and liver cancer cell(SK-Hepl) in tissue culture by the CCCA from Cordyceps militaris
- Lee, Seung-Jeong (CM Biotec) ;
-
Han, Shin-Ha
(Department of Pharmacy, Sahmyook University)
;
- Park, Eun-Jung (College of Pharmacy, Chungbuk National University) ;
- Lee, Chong-Kil (Department of Food Science, Kangnung National University) ;
- You, Byeong-Jin (Department of Biology, Seoul Women's University) ;
- Cho, Kyung-Hee (Department of Biology, Seoul Women's University) ;
- Ha, Nam-Joo (Department of Biology, Seoul Women's University) ;
- Kim, Kyung-Jae (Department of Biology, Seoul Women's University)
- Published : 2003.10.01
Abstract
Permanent cell culture lines derived from human cancer tissue are important experimental models in the study of human cancer cell proliferation. The in vitro effects of C. militaris and its extracted fractions on the human breast cancer (SK-BR3), liver cancer (SK-Hep1, HepG2), kidney cancer (p15), lymphoma (Jurkat) were studied. F1 (CCCA, crude cordycepin containing adenosine), F2 (ethanol precipitation), F3 (ethanol soluble supernatant) and F4 (fraction of through SK-1B) significantly stimulated in vitro cytotoxic in human cancer cell lines. (omitted)
Keywords