Proceedings of the Korean Society of Precision Engineering Conference (한국정밀공학회:학술대회논문집)

  • 2005.06a
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  • Pages.892-895
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  • 2005
  • /
  • 2005-8446(pISSN)
Korean Society for Precision Engineering (한국정밀공학회)
권호 표지

Detecting and Tracking Changes of Mechanical Characteristics in the Trabecular and Cortical Bone of the Lumbar Vertebrae for an Ovariectomised Rat using In-Vivo Micro-CT and Micro Finite Element Analysis

IN-VIVO MICRO-CT 와 미세 유한요소법를 이용한 쥐의 골다공증 해면골과 피질골의 구조적 특성 추적관찰 및 기계적 특성 분석

  • Ko C.Y. (Department of Biomedical Engineering. College of Health Science, Research Instrument ation Rehabilitation Engineering, Yonsei University) ;
  • Woo D.G. (Department of Biomedical Engineering. College of Health Science, Research Instrument ation Rehabilitation Engineering, Yonsei University) ;
  • Kim H.S. (Department of Biomedical Engineering. College of Health Science, Research Instrument ation Rehabilitation Engineering, Yonsei University) ;
  • Lee B.L. (Department of Anatomy. College of Medicine, Kunkuk University) ;
  • Tack G.R. (Department of Biomedical Engineering. College of Medicine, Kunkuk University)
  • 고창용 (연세대학교 보건과학대학 의공학과, 의용계측 및 재활공학 연구센터) ;
  • 우대곤 (연세대학교 보건과학대학 의공학과, 의용계측 및 재활공학 연구센터) ;
  • 김한성 (연세대학교 보건과학대학 의공학과, 의용계측 및 재활공학 연구센터) ;
  • 이법이 (건국대학교 의과대학 해부학 교실) ;
  • 탁계래 (건국대학교 의료생명대학 의학공학과)
  • Published : 2005.06.01
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Abstract

This study investigated changes of mechanical characteristics in the trabecular and cortical bone of the lumbar vertebrae of the ovariectomised(OVX) rat. In previous researches, there were many studies for morphology of osteoporotic bones based on Micro-CT (Micro - Computed Tomography). However, there were few studies for detecting and tracking changes of mechanical characteristics in the trabecular bone and cortical bone of the lumbar vertebrae for the OVX rat. For this study, one female Sprague-Dawley rat was used: an OVX rat. The 4th lumbar of the OVX rat was utilized as a specimen. Detecting and tracking changes of mechanical characteristics could be investigated in the trabecular and cortical bone of the lumbar vertebrae for an OVX rat using In-vivo Micro-CT. An OVX rat was scanned at week 0 (just before surgery), at week 4, and week 8 after surgery. Micro finite element(${\mu}\;FE$) analysis was used to investigate mechanical characteristics in the trabecular and cortical bone of the lumbar vertebrae for an OVX rat.

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