Proceedings of the Polymer Society of Korea Conference (한국고분자학회:학술대회논문집)
- 2006.10a
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- Pages.50-51
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- 2006
Preparation of PHBV/Collagen Nanofibrous Mats and their Tissue Compatibility Compatibilscaffolds for tissue engineering
- Meng, Wan (Department of Polymer Science, Kyungpook National University) ;
- Kim, Se-Yong (Department of Polymer Science, Kyungpook National University) ;
- Yuan, Jiang (Department of Polymer Science, Kyungpook National University) ;
- Kim, Jung-Chul (Department of Immunology, Kyungpook National University) ;
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Kwon, Oh-Hyeong
(Department of Polymer Science and Engineering, Kumoh National Institute of Technology)
;
- Ito, Yoshihiro (Kanagawa Academy of Science and Technology) ;
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Kang, Inn-Kyu
(Department of Polymer Science, Kyungpook National University)
- Published : 2006.10.13
Abstract
The nanofibrous scaffolds were obtained by co-electrospinning PHBV and collagen Type I in HIFP. The resulting fiber diameters were in the range between 300 and 600 nm. The nanofiber surfaces were characterized by ATR-FTIR, ESCA and AFM. The PHBV and collagen components of the PHBV-Col nanofibrous scaffold were biodegraded by PHB depolymerase and a collagenase Type I aqueous solution, respectively. It was found, from the cell-culture experiment, that the PHBV-Col nanofibrous scaffold accelerated the adhesion of the NIH 3T3 cell compared to the PHBV nanofibrous scaffold, thus showing a good tissue engineering scaffold.
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