Biocompatibilities of Some Synthetic Polymers in Films

  • Kim, Gha-Hee (Department of Chemistry, National Research Laboratory of Polymer Synthesis agnd Physics, Division of Chemistry, BK21 Progragm, and Polymer Research Institute, Pohagng University of Science and Technology) ;
  • Yoon, Jin-Hwan (Department of Chemistry, National Research Laboratory of Polymer Synthesis agnd Physics, Division of Chemistry, BK21 Progragm, and Polymer Research Institute, Pohagng University of Science and Technology) ;
  • Ree, Moon-Hor (Department of Chemistry, National Research Laboratory of Polymer Synthesis agnd Physics, Division of Chemistry, BK21 Progragm, and Polymer Research Institute, Pohagng University of Science and Technology) ;
  • Kim, Hee-Soo (Department of Microbiology, Dongguk University College of Medicine)
  • Published : 2006.10.13

Abstract

We chose three synthetic polymers, poly(propylene carbonate) (PPC), poly(vinylidene fluoride-co-hexafluoropropylene) (PVFHFP), and $Nafion^{(R)}$ that reveal different chemical and physical characteristics, and investigate their biocompatibilities to five different bacteria (that are most notorious for opportunistic and iatrogenic infections) and a human cell (HEp-2). The bacteria chosen in this study found to adhere onto the PPC and Nafion films but not to adhere on the PVFHFP film. On the other hand, both PVFHFP and Nafion films revealed good compatibility to HEp-2 and allowed the growth of the HEp-2 on the film surface but PPC showed poor compatibility to HEp-2. All results will be discussed with taking into account the surface characteristics of the polymers.

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