Proceedings of the Polymer Society of Korea Conference (한국고분자학회:학술대회논문집)

The Polymer Society of Korea (한국고분자학회)
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Radial Flow Type Bioreactor for Bioartificial Liver Assist System using PTFE Non-Woven Fabric Coated with Poly-amino Acid Urethane Copolymer

  • Miskon, Azizi (Department of Biomedical Engineering, Advanced Medical Engineering Center, National Cardiovascular Center Research Institute) ;
  • Yamaoka, Tetsuji (Department of Biomedical Engineering, Advanced Medical Engineering Center, National Cardiovascular Center Research Institute) ;
  • Uyama, Hiroshi (Department of Chemical Engineering, Osaka University) ;
  • Kodama, Makoto (Department of Biological Function and System Engineering, Kyushu Institute of Technology)
  • Published : 2006.10.13
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Abstract

PAU is the block copolymer consists of a small amount of a small amount of poly(${\gamma}-methyl-L-glutamate$) (PMLG) and the polyurethane. The urethane segments are hydrophobic and then strongly interact with the other hydrophobic materials such as PTFE, and the PMLG segments with the ${\alpha}-helix$ structure possess the cytocompatibility. Therefore, PAU can be easily coated onto the PTFE fiber and acts as an artificial extracellular matrix with the high cytocompatibility Results shows, the immobilization, cultured and functions of porcine hepatocytes is greatly improved.

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