Modified Silk Sericin Nanoparticles and Nanofibers by Electrospinning

  • Kanchanason, Vipasri (Polymer Processing and Polymer Nanomaterials Research Unit, The Petroleum and Petrochemical College, Chulalongkorn University) ;
  • Magaraphan, Rathanawan (Polymer Processing and Polymer Nanomaterials Research Unit, The Petroleum and Petrochemical College, Chulalongkorn University) ;
  • Nithitanakul, Manit (Polymer Processing and Polymer Nanomaterials Research Unit, The Petroleum and Petrochemical College, Chulalongkorn University)
  • Published : 2006.10.13

Abstract

Sericin was modified by solution blending (10-30 wt%) with 70-90 wt% polyacrylamide (PAM) in water. The reactive sites of sericin such as serine and tyrosine were attached to PAM. Proton Nuclear Magnetic Resonance ($^{1}H-NMR$) and thermogravimetric analysis were used to characterize the modified sericin. The electrospinning conditions i.e. the blend composition and the power supply voltage, at a tip to target distance of 15 cm were studied. The morphology of nanoparticles and nanofibers was observed by scanning electron microscopy. The average particles size of the nanoparticle obtained was 191 nm and nanofibers was 150-300 nm.

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