Proceedings of the Plant Resources Society of Korea Conference (한국자원식물학회:학술대회논문집)

The Plant Resources Society of Korea (한국자원식물학회)
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Production of Minor Gisenosides from Gypenoside V

Gypenoside V로부터 minor ginsenosides의 생산

  • Son, Na-Ri (Korean ginseng center for most valuable product & Ginseng Genetic Resource Bank, Kyung Hee University) ;
  • Min, Jin-Woo (Korean ginseng center for most valuable product & Ginseng Genetic Resource Bank, Kyung Hee University) ;
  • Jang, Mi (Korean ginseng center for most valuable product & Ginseng Genetic Resource Bank, Kyung Hee University) ;
  • Kim, Hyo-Yeon (Korean ginseng center for most valuable product & Ginseng Genetic Resource Bank, Kyung Hee University) ;
  • Jeon, Ji-Na (Korean ginseng center for most valuable product & Ginseng Genetic Resource Bank, Kyung Hee University) ;
  • Yang, Deok-Chun (Korean ginseng center for most valuable product & Ginseng Genetic Resource Bank, Kyung Hee University)
  • 손나리 (경희대학교 고려인삼 명품화 사업단 & 인삼유전자은행) ;
  • 민진우 (경희대학교 고려인삼 명품화 사업단 & 인삼유전자은행) ;
  • 장미 (경희대학교 고려인삼 명품화 사업단 & 인삼유전자은행) ;
  • 김효연 (경희대학교 고려인삼 명품화 사업단 & 인삼유전자은행) ;
  • 전지나 (경희대학교 고려인삼 명품화 사업단 & 인삼유전자은행) ;
  • 양덕춘 (경희대학교 고려인삼 명품화 사업단 & 인삼유전자은행)
  • Published : 2010.10.07
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Abstract

Panax ginseng C.A Meyer is frequently taken orally as a traditional herbal medicine in Asian countries. The major components of ginseng are ginsenoside, which are pharmaceutical activity. The six major ginsenosides, including Rb1, Rb2, Rc, Rd, Re and Rg1 account for 90% of total ginsenosides. Even though the minor ginsenosides, including Rg3, Rh2 and compound K has high pharmacetical activities, the price of minor ginsenosides is too high. Therefore we isolated the gypenoside V and made it converted to minor ginsenosides. In the plant Gynostemma pentaphyllum Makino, gypenosdie V was presented as dominant saponin (content about 2.4%), and was similar to protopanaxadol type ginsenosides such as ginsenoside Rb1. In this study, we confirmed that the coversion of gypenoside V to minor ginsenosides after using the various treatment such as heating, acid treatment, commercial edible enzyme, and lactobacillus. Consequently, we optimizied the transformation of gypenoside V to minor ginsenoside using Thin Layer Chromatography (TLC), High Performance Liquid Chromatography (HPLC), Time-of-flight Mass Spectrometry (LC/TOF/MS).

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