Effect of Iodine-131 Administration on the Liver of Guinea Pig

방사성 옥소(131I)가 Guinea Pig의 간장에 미치는 영향

  • Published : 1972.04.30

Abstract

This experiment was carried out to investigate the effect on the liver of guinea pig after administration of 4.5mCi per Kg. body wt. with iodine-131. The histological changes in the liver were degeneration of hepatic cells, congestion of sinusoids, dilatation of bile ducts, perivascular infiltration of lymphocytes, and dissociation of hepatic cords. A marked histological changes were produced after treatment for 14 days and the morphological recoveries were observed 28 days after the treatment.

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