A Comparison of Alcohol Toxicity on Rats and Frogs

흰쥐와 개구리에 대한 Alcohol 독성의 비교

The comparison of topic effects of methanol and ethanol on rats and frogs was performed. Intraperitoneal administration in graded doses of absolute alcohols showed specific toxicities on animals, suggesting that these substances had different effects on species specificity of animals. Throughout the experiment, the following results were obtained and summerized here. 1. In rats $LD_{50}$ dose of absolute methanol was $2.65{\mu}l/g$ of body weight, while that of absolute ethanol was $1.85{\mu}l/g$ of body weight. 2. The $LD_{50}$ dose of methanol in frogs was $17.2{\mu}l/g$ of body weight, while that of ethanol was $10.9{\mu}l/g$ of body weight.