Studies on the Synthesis and Antibacterial Activity of PAS-Sulfonamide Derivatives

PAS-Sulfonamide 유도체의 합성 및 항균력에 관한 연구

Twelve derivatives of PAS-sulfonamide were synthesized and tested for their antibacterial activity against various bacterial strains. The derivatives XII and XIV showed relatively potent antibacterial activity to INAH-R strains and INAH-PAS-R strains and type XII to streptococcal strains; type IX and type VI to Pseudomonas aeruginosa.