Korean Journal of Microbiology (미생물학회지)
- Volume 17 Issue 3
- /
- Pages.152-159
- /
- 1979
- /
- 0440-2413(pISSN)
- /
- 2383-9902(eISSN)
Production of Gentamicin by Micromonospora purpurea
Micromonospora purpurea에 의한 gentamicin생성
Abstract
Using Micromonospora strain, gentamicin was produced by fermentation. The increase in gentamicin productivity was studied by strain improvement and systematic optimization of fermentation process variables. The productivity of parent strain of M.purpurea (ATCC15835) was improved by selection of superior mutant after U.V. irradiation and induction of genetamicin resistance. Potato starch and soy bean meal were the best carbon and nitrogen sources for gentamicin fermentation, respectively. The optimum stimulating concentration of Co ion for gentamicin production was 0.006g
Keywords