Effects of Reductions in Renal Mass on Blood Urea Nitrogen and Serum Creatinine Concentrations in dogs

신장(腎臟)mass 감소(減少)가 혈액요소질소(血液尿素窒素)와 혈청(血淸) 크레아티닌 농도(濃度)에 미치는 영향

Renal dysfunction was experimentally induced with reductions in renal mass in dogs and then the remaining kidney function was estimated by blood urea nitrogen and serum creatinine concentrations. During experimental period, blood urea nitrogen and serum creatinine concentrations showed no variance in dogs with 50% reductions in renal mass, but these values were remarkably increased in dogs with 75% reductions in renal mass. It was considered that 75% reductions in renal mass was applicable as experimental models for renal dysfunction.