Effect of Dietary Fat Sources and Levels on Plasma and Tissue Cholesterol

식이내 지방의 종류와 수준이 혈장 콜레스테롤 및 조직내 콜레스테롤 함량에 미치는 영향

The present studies were designed to compare the effects of dietary fat sources and levels on plasma and tissue cholesterol. Changes in plasma total cholesterol and HDL-cholesterol, cholesterol concentration in aortas, liver and intestines were determined in young rats fed diets providing dietary fat as corn-oil or butter and levels as 10%, 20% or 30% of calories respectively 1) Plasma total cholesterol and HDL-cholesterol levels were little sensitive to the modification of dietary fat sources and levels. 2) Dietary cholesterol increased the levels of plasma total cholesterol and this effect was accentuated by feeding butter. But dietary cholesterol did not increase the levels of HDL-cholesterol in the butter-fed groups, but decreased in the corn-oil-fed groups. 3) Liver cholesterol concentrations were significantly higher in rats fed diets of corn-oil than those fed diets of butter. On the contrary, cholesterol concentrations of intestines were significantly higher in the butter-fed groups than the corn-oil-fed groups. However, in aortas, no significant differences were found.