Archives of Pharmacal Research
- Volume 7 Issue 1
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- Pages.41-45
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- 1984
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Effects of red ginseng-crude saponin on plasma liqid levels in rats fed on a diet high in cholesterol and triglyceride
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Moon, Chang-Kiu
(College of Pharmacy, Seoul National University) ;
- Kang, Nae-Young (College of Pharmacy, Seoul National University) ;
- Yun, Yeo-Pyo (College of Pharmacy, Seoul National University) ;
- Lee, Soo-Hwan (College of Pharmacy, Seoul National University) ;
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Lee, Hyun-Ah
(College of Pharmacy, Seoul National University) ;
- Kang, Tak-Lim (Department of Pharmacy , Dong-Duck Womens College)
- Published : 1984.06.01
Abstract
The effect of Red ginseng saponin on plasma lipid levels in Wistar rats fed on a diet high in cholesterol and triglyceride was determined. A dose of Red ginseng-crude saponin (150 mg/kg/day) was administered orally for 4 weeks to Wistar rats fed on a diet containing 2% cholesterol and 10% olive oil. Plasma levels of total cholesterol, HDL-cholesterol and triglyceride were measured and lipoproteins were analyzed by using electrophoretic technique. Red ginseng saponin showed no significant changes of HDL-cholesterol level but it lowered plasma levels of total cholesterol and elevate those of triglyceride intensively.
Keywords
- Red ginseng saponin;
- Lipoprotein;
- Hy-pocholesterolemic effect;
- Hypertriglyceridemic effect;
- HDL-cholesterol