Archives of Pharmacal Research
- Volume 7 Issue 2
- /
- Pages.127-132
- /
- 1984
- /
- 0253-6269(pISSN)
- /
- 1976-3786(eISSN)
Pharmacological Study on Piperine
-
Lee, Eun-Bang
(Natural Products Research Institute, Seoul National University)
;
-
Shin, Kuk-Hyun
(Natural Products Research Institute, Seoul National University)
;
- Woo, Won-Sick (Natural Products Research Institute, Seoul National University)
- Published : 1984.12.01
Abstract
Systematic pharmacological astudies on pipeline have revealed that this compound elicited diverse pharmacological activities; CNS depressant activity characterized by antagonism against electo shock seizure and by muscle relaxant activity in mice; antipyretic activity in tyyhoid vaccinated rabbits; analgesic activity as evaluated by tail-clip pressure and writhing syndrome in mice; antiinflammatory activity in carrageenin-induced edema in rats.
Keywords
- Piperine;
- CNS;
- depressant activity;
- Antipyretic activtity;
- Analgesic activtiy;
- Antiinfalmmatory activity