Korean Journal of Food Science and Technology (한국식품과학회지)

Korean Society of Food Science and Technology (한국식품과학회)
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Desmutagenic Effect of Legumes and Plants Crude Saponins in Salmonella typhimurium TA 98

콩과 식물에서 추출한 사포닌의 돌연변이원성 억제효과

  • Ryu, Beung-Ho (Department of Food Science and Technology, College of Science and Engineering, Busan San Ub University) ;
  • Lee, Beung-Ho (Department of Nutrition, College of Home Economics, Dong Eui University) ;
  • Ha, Mi-Suck (Department of Food Science and Technology, College of Science and Engineering, Busan San Ub University) ;
  • Kim, Dong-Seuk (Department of Food Science and Technology, College of Science and Engineering, Busan San Ub University) ;
  • Sin, Dong-Bun (Department of Food Science and Technology, College of Science and Engineering, Busan San Ub University) ;
  • Nam, Ki-Du (Department of Food Science and Technology, College of Science and Engineering, Busan San Ub University)
  • 류병호 (부산산업대학교 이공대학 식품공학과) ;
  • 이병호 (동의대학교 가정대학 식품영양학과) ;
  • 하미숙 (부산산업대학교 이공대학 식품공학과) ;
  • 김동석 (부산산업대학교 이공대학 식품공학과) ;
  • 신동분 (부산산업대학교 이공대학 식품공학과) ;
  • 남기두 (부산산업대학교 이공대학 식품공학과)
  • Published : 1986.10.01
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Abstract

Crude saponins of soybean and Azuki bean (2.0 mg/plate)were most effective against Trp-p-2, and also all of legume saponins (2.0 mg/plate)were excellent effective against aflatoxin $B_1$. Crude saponins of taro, burdock and ginseng were remarkably effective at ranging from 1.0 mg to 2.0 mg per plate against MeIQ. Especially ginseng saponin was excellent effective and arrow root saponins was remarkably effective against MeIQ, respectively. Plant saponins of taro, lotus burdock, arrow root and ginseng except for dodok were most effective activities against aflatoxin $B_1$.

4종과 콩과 6종의 식물에서 추출한 사포닌을 methyl-5H-pyrido[4, 3-b] indole(T-p-2), 3-amino-1-methyli-midazo[4, 5-f] guinoline(MeIQ) 및 Aflatoxin $B_1$을 이용하여 Salmonella typhimurium TA 98로서 돌연변원성 억제효과를 검토하였다. 콩과 팥의 사포닌(2.0 mg/plate)은 aflatoxin $B_1$에 좋은 효과를 나타내었고 6종의 식물의 사포닌을 대부분 돌연변이원성 억제효과가 우수하였다. 식물에서 추출한 사포닌 중 토란, 우엉 그리고 인삼사포닌은($1.0{\sim}2.0\;mg/plate$)은 MeIQ에 현저한 효과를 나타내었고, 특히 인삼과 칡의 사포닌은 우수한 돌연변이원성 억제효과를 나타내었다. Aflatoxin $B_1$에 대한 돌연변이원성 억제효과는 더덕을 제외한 식물성 사포닌은 좋은 효과를 나타내었다.

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