Effect of Pollen Load on Chloroform-induced Hepatic and Renal Damage in Rats -Concerning Pathohibtological Aspects-

Chloroform에 의한 Rat 간(肝) 및 위장(胃臟) 장해(障害)에 미치는 화분립(花粉粒)의 영향(影響) -병리조직학적 소견-

  • Kwon, Chong-Suk (Dept. of Home Economics, Andong National College) ;
  • Yoon, Soo-Hong (Lab. of Hygine, College of Pharmacy, Hyosung Women's University)
  • Published : 1986.09.30

Abstract

The present experiment was intended to determine the effect of pollen load on chloroform-induced hepatic and renal damage in albino rats. The subjects were administered with the graded concentration of chloroform and an additional amount of pollen load to some groups, and the result of which was: 1. Fatty changes and necrosis in liver and kidneys of the experimental group became more severe according to the chloroform concentration. 2. The tissue damage decreased in the pollen-treated groups. But the higher the concentration of chloroform administered with pollen is, the less the damaged tissue is rehabilitated.

화분립(花粉粒)의 chloroform으로 인한 간(肝) 및 위장조직(胃臟組織)에 미치는 영향을 알기 위해 rat에 농도별로 chloroform을 투여하고 또 이들과 화분립(花粉粒)을 함께 투여(投與)한 결과, chloroform 농도가 증가할 수록 조직파괴 및 지방변성이 심했으며, 화분립(花粉粒)을 함께 투여(投與)함으로 조직파괴 정도가 약화됨을 알 수 있었고, 화분립(花粉粒)과 함께 투여(投與)하는 chloroform의 농도가 낮을수록 대조군(對照群)의 조직(組織)에 가까운 형태로 회복됨을 볼 수 있었다.

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