Analysis of Left Ventricular Diastolic Function in Coronary Artery Disease with Gated Blood Pool Scan

관상동맥질환에서 Gated Blood Pool Scan을 이용한 좌심실 확장기능의 분석

  • Choi, Chang-Woon (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Lim, Sang-Moo (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Chung, June-Key (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Lee, Myung-Chul (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Park, Young-Bae (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Seo, Joung-Don (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Lee, Young-Woo (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Koh, Chang-Soon (Department of Internal Medicine, College of Medicine, Seoul National University)
  • 최창운 (서울대학교 의과대학 내과학교실) ;
  • 임상무 (서울대학교 의과대학 내과학교실) ;
  • 정준기 (서울대학교 의과대학 내과학교실) ;
  • 이명철 (서울대학교 의과대학 내과학교실) ;
  • 박영배 (서울대학교 의과대학 내과학교실) ;
  • 서정돈 (서울대학교 의과대학 내과학교실) ;
  • 이영우 (서울대학교 의과대학 내과학교실) ;
  • 고창순 (서울대학교 의과대학 내과학교실)
  • Published : 1986.12.31

Abstract

Resting gated blood pool scan was used to derive left ventricular functional changes in normals (N=13, mean age=43) and in patients with coronary artery disease (N=50, mean age=53). Peak filling rates, average filling rates, and ejection fractions were significantly depressed in coronary artery disease. (p<0.0005, each other). And in coronary artery disease with normal ejection fraction (N=21), peak filling rates and average filling rates were depressed also, and peak filling rates of coronary artery disease with normal ejection fraction were abnormal in 61.2% and average fillin rates were abnormal in 71.4%. It appears that (1) resting peak filling rates and average filling rates were sensitive and easily obtainable parameters of the diastolic dysfunction assosiated with coronary artery disease, (2) a significant proportion of coronary artery disease patients without any evidence of abnormal systolic function have depressed resting peak filling rates and average filling rates of the left ventricle.

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