Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)
- Volume 3 Issue 1
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- Pages.43-47
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- 1986
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- 1225-9098(pISSN)
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- 2288-1069(eISSN)
DOI QR Code
Synthesis and Antioxidant Activities of 1, 2-bis(aminoacyl) hydrazine derivatives
1, 2-bis(aminoacyl)hydrazine 유도체들의 합성과 항산화 효과
- Kang, Shin-Won (Dept. of Chem. Pusan National University) ;
- Lee, Sang-Un (Dept. of Chem. Pusan National University) ;
- Shin, Hong-Dae (Dept. of Chem. Pusan National University)
- Published : 1986.05.31
Abstract
1.2-bis(aminoacyl)hydrazine derivatives and dipeptides were synthesized by conventional peptide synthesis procedures. Their antioxidant activity were inverstigated by over-storage test using corn oil as substrte. 1.2-bis (aminoacyl) hydrazine derivatives and dipetides containing hydrophobic side chain amino acid showed higher antioxidant activity. A free N-terminal amino group was also found to be important for the appearance of antioxidant activity. 1.2-bis (aminoacyl) hydrazine derivatives showed higher antioxidant activity than dipeptides. Antimicrobial activites of dipeptides and 1.2-bis (aminoacyl) hydrazine derivatives were also examined by the paper disc method. All of these compounds had shown no antimicrobial activity.
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