Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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Chemically-Induced Delayed Cutaneous Hypersensitivity in Guinea Pigs and Rabbits Experimentally Infected with Mycobacterium bovis

Mycobacterium bovis 감염(感染)이 화학적(化學的)으로 유발(誘發)된 지연형(遲延型) 피부과민증(皮膚過敏症)에 미치는 영향(影響)

  • Lee, Chai-yong (Department of Veterinary Medicine, College of Agriculture, Chonnam National University) ;
  • Lee, Chung-gil (Department of Veterinary Medicine, College of Agriculture, Chonnam National University) ;
  • Park, Young-jun (Department of Veterinary Medicine, College of Agriculture, Chonnam National University)
  • 이채용 (전남대학교 농과대학 수의학과) ;
  • 이정길 (전남대학교 농과대학 수의학과) ;
  • 박영준 (전남대학교 농과대학 수의학과)
  • Received : 1986.07.23
  • Published : 1986.10.25
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Abstract

In order to evaluate the effects of the cell-mediated immunity of the animal in the chronic diseases the guinea pigs and rabbits were inoculated with Mycobacterium bovis. After 6 weeks these animals were sensitized and challenged with 2,4-dinitrochlorobenzene. The cutaneous reactions observed in these animal species were similar each other. Macroscopic and microscopic responses in the animal experimentally infected with M. bovis were markedly reduced compared to those in the control animals. The results indicated that the cell-mediated immunity of the animals was depressed by infection of M. bovis.

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