A Delayed Cutaneous Hypersensitivity Induced with 2, 4-Dinitrochlorobenzene in Ducks and Chickens

2, 4-Dinitrochlorobenzene으로 유발(誘發)된 오리와 닭의 지연형(遲延型) 피부과민증(皮膚過敏症)

  • Lee, Chai-yong (Department of Veterinary Medicine, College of Agriculture, Chonnam National University) ;
  • Lee, Chung-gil (Department of Veterinary Medicine, College of Agriculture, Chonnam National University) ;
  • Lee, Joo-muk (Department of Veterinary Medicine, College of Agriculture, Chonbuk National University)
  • 이채용 (전남대학교 농과대학 수의학과) ;
  • 이정길 (전남대학교 농과대학 수의학과) ;
  • 이주묵 (전북대학교 농과대학 수의학과)
  • Received : 1986.02.27
  • Published : 1986.04.30

Abstract

An experiment was carried out to measure the cellular immune response in the animals by sensitizing the animals with 2, 4-dinitrochlorobenzene(DNCB). The fowls could be sensitized with primary application of DNCB. The sensitizing and challenge dose was standardized. Heterophils were prominent in the early inflammatory response in the superficial and deep dermal regions with scattering of eosinophils. The histological response in the fowls was characteristic of a delayed hypersensitivity reaction.

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