생약복합제제(生藥複合製劑)의 약효연구(藥效硏究)(제37보)(第37報) -천왕보심단(天王補心丹)이 중추신경계(中樞神經系) 및 순환기계(循環器系)에 미치는 영향(影響)-

Studies on the Efficacy of Combined Preparation of Crude Drugs(XXXVII) -The effects of Chunwangboshimdan on the central nervous system and cardio-vascular system-

To investigate the experimental effects of Chunwangboshimdan which have been widely used for aterial or auricular flutter, neurosis, insomnia and disease caused by cardiac malfunction, we have done the effects on the central nervous and cardiovascular system. The result as follow; It inhibited the convulsion induced by caffeine, the writhing syndrome induced by acetic acid and the spontaneous movement. Furthermore it prolonged the sleeping time induced by thiopental-Na in mice. It also showed the negative inotropic action on the isolated heart of frog, the vasodilative action as to peripheral bloods of rabbit ear and the hypotensive action in the anesthetized rabbit.