Korean Journal of Pharmacognosy (생약학회지)
- Volume 19 Issue 4
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- Pages.256-261
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- 1988
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Studies on the Uterotonic Action of N-Butanol Extracts from Dianthi Herba
패랭이꽃 N-Butanol 추출물의 자궁수축작용에 관한 연구
- Huh, Keun (College of Pharmacy, Yeungnam University) ;
- Ryu, Hang-Mook (National Institute Safety Research Division of Reproductive Toxicology) ;
- Lee, Sang-Il (Department of Food and Nutrition, Keimyung Junior College) ;
- Park, Jong-Min (College of Pharmacy, Yeungnam University) ;
- Song, Jae-Woong (College of Pharmacy, Yeungnam University) ;
- Shin, Uk-Seob (College of Pharmacy, Yeungnam University)
- 허근 (영남대학교 약학대학) ;
- 류항묵 (국립보건안전연구원 생식독성과) ;
- 이상일 (계명실업전문대학 식품영양학과) ;
- 박종민 (영남대학교 약학대학) ;
- 송재웅 (영남대학교 약학대학) ;
- 신억섭 (영남대학교 약학대학)
- Published : 1988.12.30
Abstract
The present studies were investigated to find out the uterus contractive components and action mechanism of contractive components. We observed that the contractive components of Dianthi Herba were extracted with methanol and dissolved in butanol. The butanol extracts of Dianthi Herba increased uterus contractility, and fraction 2 obtained from butanol extract was more powerful than other fractions. This action was not blocked by atropine, papaverine, prazosin, propranolol, chlorpheniramine, methysergide and diltiazem in vitro.