Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Effect of Cuscutae extract on experimentally induced liver damage in rabbits

토사자 추출물이 실험적으로 유발된 가토의 간장기능장애에 미치는 영향

  • 이명렬 (조선대학교 식품영양학과) ;
  • 전성주 (조선대학교 식품영양학과)
  • Published : 1989.09.30
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Abstract

This study was carried out to investigate effects of Cuscutae semen extract(C. S. E) on $CCI_4$-induced liver damage in rabbits and acute toxicity in mice. $LD_{50}(mg/kg)$ of C. S. E. was 7.83g/kg by intraperitoneal administration in mice. C. S. E. groups were showed more rapid recuperation than the control group intoxicated by $CCI_4$ only. SGPT activity was lowered significantly in 800mg/kg after 6 days. The levels of total cholesterol and total bilirubin and alkaline phosphatase were decreased apparently in 800mg/kg from 6 days. It is suggested that C. S. E. can be administered not only as a therapeutic agent(such as liver tonics) but also a healthy food to shorten the recovery time in liver diseases.

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