The Korean Journal of Nuclear Medicine (대한핵의학회지)

The Korean Society of Nuclear Medicine (대한핵의학회)
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Diagnostic Accuracy of $^{99m}Tc-Pyrophosphate$ Scan in Acute Myocardial Infarction

급성 심근 경색증에서의 $^{99m}Tc-Pyrophosphate$ Myocardial Scan의 양성율에 대한 연구

  • Koong, Sung-Soo (Department of Internal Medicine, College of Medicine, Chungbuk National University) ;
  • Kim, Seung-Taik (Department of Internal Medicine, College of Medicine, Chungbuk National University) ;
  • Moon, Dae-Hyuk (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Chung, June-Key (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Lee, Myung-Chul (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Cho, Bo-Youn (Department of Internal Medicine, College of Medicine, Seoul National University) ;
  • Koh, Chang-Soon (Department of Internal Medicine, College of Medicine, Seoul National University)
  • 궁성수 (충북대학교 의과대학 내과학교실) ;
  • 김승택 (충북대학교 의과대학 내과학교실) ;
  • 문대혁 (서울대학교 의과대학 내과학교실) ;
  • 정준기 (서울대학교 의과대학 내과학교실) ;
  • 이명철 (서울대학교 의과대학 내과학교실) ;
  • 조보연 (서울대학교 의과대학 내과학교실) ;
  • 고창순 (서울대학교 의과대학 내과학교실)
  • Published : 1989.05.31
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Abstract

To evaluate diagnostic accuracy of $^{99m}Tc-pyrophosphate$ (PYP) myocardial scan, we analysed 160 $^{99m}Tc-PYP$ scans (acute transmural myocardial infarction 87 cases, acute subendocardial infarction; 20 cases, unstable angina pectoris; 7 cases, other disease; 46 cases). These scans were requested by the physician in Seoul National University Hospital from Sep. 1982 to Oct. 1987. And the diagnosis was confirmed by clinical course and laboratory examinations. 1) The diagnostic sensitivity of $^{99m}Tc-PYP$ scan in acute transmural myocardial infarction was 91.2% (62/68) if scintigraphy was performed within 7 days after infarction, 57.1% (8/14) between 8th and 14th day, 20% (1/5) and after 15 days. 2) The diagnostic sensitivity of $^{99m}Tc-PYP$ scan in acute subendocardial infarction was 75% (12/16) if scintigraphy was performed within 7 days after infarction and 0% after 8 days. 3) The diagnostic specificity of $^{99m}Tc-PYP$ scan in acute myocardial infarction was 94.3% (5/53). Among 5 cases of false positive scans, 1 case was unstable angina pectoris, 2 cases were old myocardial infarction with left ventricular aneurysm, 1 case was old myocardial infarction and the remaining 1 case was cardiomyopathy.

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