약학회지 (YAKHAK HOEJI)
- 제34권6호
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- Pages.401-406
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- 1990
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
신장장해 가토에서 Furosemide의 약물동태
Pharmacokinetics of Furosemide in Rabbits with Renal Failure
- Choi, Jun-Shik (College of Pharmacy, Chosun University) ;
- Choi, Tou-Ma (College of Pharmacy, Chosun University) ;
- Lee, Jin-Hwan (College of Pharmacy, Chosun University) ;
- Burm, Jin-Pil (College of Pharmacy, Chosun University)
- 발행 : 1990.12.28
초록
The Pharmacokinetics of furosemide (5 mg/kg iv) was investigated in rabbits with folate (75 mg/kg, 150 mg/kg 300 mg/ug, iv) induced renal failure. The plasma concentration was increased and urinary excretion was decreased significantly compared with those of normal rabbits.