Archives of Pharmacal Research
- Volume 13 Issue 2
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- Pages.126-131
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- 1990
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Synthesis and Cycloaddition Reactions of N-Aryl-2-furohydrazonyl Chlorides
- S, Shawali-Ahmad (Department of Chemistry, Faculty of Science, King Abdulaziz University) ;
- M, Hassaneen-Hamdi (Department of Chemistry, Faculty of Science, University of Cairo) ;
- A, Ibrahim-Hossin (Department of Chemistry, Faculty of Science, University of Cairo)
- Published : 1990.06.01
Abstract
The novel N-phenyl-2-furohydrazonyl chloride 4A and its p-nitro analog 4B have been prepared and identified. The cycloaddition reactions of nitrilimines 5A and 5B, derived by base catalyzed dehydrochlorination of 4A and 4B respectively, to a variety of dipolarophiles were investigated. The results showed that 4A and 4B are usuful precursors for synthesis of differently substituted 3-(2-furyl)-2-pyrazoline derivatives and their pyrazoles and analogs.