The Korean Journal of Physiology
- Volume 25 Issue 2
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- Pages.179-188
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- 1991
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- 0300-4015(pISSN)
Inhibition of Dicarboxylate Transport by p-chloromercuribenzoic Acid (PCMB) in Plasma Membrane Vesicles of Rabbit Proximal Tubule
- Kim, Yong-Keun (Department of Physiology, College of Medicine, Pusan National University) ;
- Kim, Tae-In (Department of Physiology, College of Medicine, Pusan National University) ;
- Jung, Jin-Sup (Department of Physiology, College of Medicine, Pusan National University) ;
- Lee, Sang-Ho (Department of Physiology, College of Medicine, Pusan National University)
- Published : 1991.12.01
Abstract
Effect of a sulfhydryl reagent, p-chloromercuribenzoic acid (PCMB), on the transport of succinate was studied in brush border (BBMV) and basolateral (BLMV) membrane vesicles isolated from rabbit renal cortex. PCMB induced an irreversible inhibition of the
Keywords
- Brush border membrane;
- Basolateral membrane;
- Dicarboxylate transport;
- Sulfhydryl group;
- PCMB;
- Rabbit proximal tubule