Archives of Pharmacal Research

  • 제14권1호
  • /
  • Pages.93-95
  • /
  • 1991
  • /
  • 0253-6269(pISSN)
  • /
  • 1976-3786(eISSN)
대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

Hepatoprotective Effects of Andrographis paniculata against Carbon Tetrachloride-Induced Liver Damage

  • Rana, A.C. (College of Pharmacy, Shri Govindram Seksaria Institute of Technology and Science) ;
  • Avadhoot, Y. (College of Pharmacy, Shri Govindram Seksaria Institute of Technology and Science)
  • 발행 : 1991.03.01
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초록

Alcoholic extract of the leaves of Andrographis paniculata Ness (=AAP) was obtained by cold maceration. A dose of 300 mg/kg $(1/6of\;LD_{50})$ of the extract was selected to study hepatoprotective action against carbon tetrachloride-induced liver damage. The extract was found to be effective in preventing liver damage which was evident by morphological, biochemical and functional parameters.

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