Synthetic $\beta$-Lactam Antibiotics V. Antibacterial Activity of Some 7$\beta$[2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido]-3-(quinolinium)thiomethylcephalosporins

  • Lim, Dong-Yeol (Organic Synthesis Lab, Korea Institute of Science and Technology) ;
  • Park, Sang-Woo (Organic Synthesis Lab, Korea Institute of Science and Technology) ;
  • Kim, You-Seung (Organic Synthesis Lab, Korea Institute of Science and Technology)
  • Published : 1991.09.01

Abstract

In the field of cephalosporins, introduction of quaternary heterocyclic methyl goups at the C-3 position has led to a new class of cephalosporins such as cefepime and cefpirome, the so-called 4th generation cephalosporins which are characterized by their potent activity. Since than many efforts were attempted to synthesize more effective analogs.

Keywords