미생물학회지 (Korean Journal of Microbiology)
- 제29권3호
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- Pages.160-166
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- 1991
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- 0440-2413(pISSN)
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- 2383-9902(eISSN)
Streptomyces tubercidicus에서 Adenine과 Histidine에 의한 Tubercidin 생합성 조절
Regulation of Tubercidin Biosynthesis in Streptomyces tubercidicus by Adenine and Histidine
초록
The regulatory mechanism of tubercidin biosynthesis in Streptomyces tubercidicus was studied. In a wild type strain, addition of adenine and histidine into the medium decreased the tubercidin production by 60-65% and 40%, respectively. The effects of adenine and histidine were alleviated by the addition of inosine monophosphate and 5-aminoimidazole-4-carboxamide ribotide. The production of tubercidin in S. tubercidicus K115 strain (