Studies on the Detoixicating Effect of Water Extracts of Scutelleria Radix in Lead Poisioning

황금수침액의 연중독 해독효과에 관한 연구

  • Jung, Chan (College of Medicine, Kyung Buk National University) ;
  • Min, Kyung-Jin (College of Natural Science, Keimyung University) ;
  • Kang, Hoe-yang (College of Natural Science, Keimyung University)
  • 정찬 (경북대학교 의과대학) ;
  • 민경진 (계명대학교 자연과학대학) ;
  • 강회양 (계명대학교 자연과학대학)
  • Published : 1991.10.01

Abstract

Lead acetate solution were intraperitoneally injected to rats of average body weight 220g to cause lead poisoning. Antidotes were orally administered using catheter to the rats and the urine was collected after 24 hours. ALA in the urine were determined by U. V. spectrophotometer. Antidotes used in this experiment were the water extracts of scutellaria radix and D-penicillamine solution. ALA in the urine was determind by Wada method. It was found that ALA content in the urine was decreased after oral administration of water extracts of scutellaria radix and D-penicillamine solution. In this study it is believed that water extract of suctellaria radix could be used as an excellent antidate in lead poisoning.

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