Archives of Pharmacal Research
- Volume 15 Issue 2
- /
- Pages.169-175
- /
- 1992
- /
- 0253-6269(pISSN)
- /
- 1976-3786(eISSN)
Lymphoblastosis Inhibition and Plaque-forming Cell Response of Several Anti-inflammatory Steroids in Mice
- Choi, Hong-Pil (College of Pharmacy, Kangweon National University) ;
- Kim, Kilhyoun (Genetic Engineering Research Institute) ;
- Kim, Hyun-Pyo (College of Pharmacy, Kangweon National University)
- Published : 1992.06.01
Abstract
Anti-inflammatory glucocorticoid (GC) derivatives have been clinically used in immune-malfunctional diseases for their immunosuppressive activity. However, there is still a lack of knowledge on the relationship between anti-inflammatory and immunosuppressive activities. In order to compare immunosuppressive activities with the known anti-inflammatory activities of the GC derivatives, eight clinically used GC derivatives including hydrocortisone, prednislone, 6
Keywords
- Glucocoricoid;
- steroid;
- anti-inflammation;
- immunosuppression;
- receptor binding affinity;
- lymphoblastosis inhibition;
- plaque-forming cell