Archives of Pharmacal Research
- Volume 15 Issue 4
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- Pages.283-288
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- 1992
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Immunomodulating Activities of Brazilin in vitro
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Moon, Chang-Kiu
(College of Pharmacy, Seoul National University)
;
- Mock, Myung-Soo (College of Pharmacy, Seoul National University) ;
- Yang, Kyung-Mee (College of Pharmacy, Seoul National University) ;
- Han, Hye-Seung (College of Pharmacy, Seoul National University) ;
- Won, Hyeon-Soon (College of Pharmacy, Seoul National University) ;
- Kim, Ji-Young (College of Pharmacy, Seoul National University) ;
-
Chung, Jin-Ho
(College of Pharmacy, Seoul National University)
;
-
Moon, Chang-Hyun
(School of Medicine, Ajou University)
- Published : 1992.12.01
Abstract
This work was performed to investigate the effects of brazilin in vitro on mitrogen-induced proliferation, ConA-induced TCGF release and responsiveness to recombinant-induced proliferation, ConA-induced TCGF release and responsiveness to recombinant IL-2 using splenocytes from C57BL/6 female mice. Brazilin (29-80 ng/ml) caused a noticeable increase in TCGF production of splenocytes, but did not affect responsivness to recombinant IL-2, the expression of ConA-induced high affinity IL-2 receptor and mitogen-induced proliferation of splenocytes.
Keywords