한국자원식물학회지 (Korean Journal of Plant Resources)

  • 제5권2호
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  • Pages.95-103
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  • 1992
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  • 1226-3591(pISSN)
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  • 2287-8203(eISSN)
한국자원식물학회 (The Plant Resources Society of Korea)
권호 표지

천연항종양성자원 とスクリニングの 실제

Practices of Antitumor Screening Tests for Natural Products

  • 발행 : 1992.11.01
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초록

Present anticancer drugs in the clinical side have not showed a conclusive effect of the chemotherapy for cancer patients. In order to find much more efficient antitumor agents fromnatural resources, various screening methods vivo and in vitro have been developed by manyresearchers. The intention of this paper is to provide an outline of some background on the tumorsystem in drug development of natural products, to review some screening programs for theevaluation of antitumor activity and to introduce the practical procedures of some antitumorscreening methods in vivo and in vitro. At the end of this paper, the current literatures related toantitumor natural products from higher plants at our laboratory are described.Key words'anticancer drugs, screening methods.

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참고문헌

  1. Chem. Pharm. Bull. v.40 no.5 New Antitumor Bicyclic Hexapeptides Ra-XI, -XII ,-XIII and -XIV from Rubia cordifolia H.Morita;T.Yamamiya;K.Takeya;H.Itokawa
  2. Sesquiterpene Pyridine Alkaloids from Maytenus ebenifolia v.34 no.5 H.Itokawa;O.Shirota;H.Morita;K.Takeya
  3. Chem. Pharm. Bull. v.40 no.4 Cytotoxic Quassinoids and Tyrucallane-Type Triterpenes from Eurycoma longifolia H.Itokawa;E.Kishi;H.Morita;K.Takeya
  4. Chem. Pharm. Bull. v.40 no.4 Solution Forms of an Antitumor Cyclic Hexapeptides RA-VII in Dimethyl Sulfoxide-$d_6$ from Nuclear Magnetic Resonance Studies H.Itokawa;H.Morita;K.Takeya
  5. Phytochemistry v.31 no.3 Cytotoxic Naphthoquinones from Mansoa alliacea H.Itokawa;K.Matsumoto;H.Morita;K.Takeya
  6. J. Chem. Soc. Perkin. Trans. v.I New Antitumour Bicyclic Hexapeptide RA-XI and -X from Rubia cordifolia. Part 3. Conformation-Antitumour Activity Relationship H.Itokawa;T.Yamamiya;H.Morita;K.Takeya
  7. Chem. Lett. A New Squalene-type Triterpene from the woods of Eurycoma longifolia H.Itokawa;E.Kishi;H.Morita;K.Takeya;Y.Iitaka
  8. Chem. Lett. RAI-III and -VI, Conformational Isomers of Antitumorur Cyclic Hexapeptides, RA-III and -VI from Rubia cordifolia H.Itokawa;H.Morita;K.Takeya;N.Tomioka;A.Itai
  9. Tetrahedron v.47 no.34 New Antitumor Bicyclic Hexapeptides, RA-VI and -VIII from Rubia cordifolia; Conformation-Activity Relationship II H.Itokawa;H.Morita;K.Takeya;N.Tomioka;A.Itai;Y.Iitaka
  10. Phytochemistry v.30 no.11 Triterpenes from Maytenus ilicifolia H.Itokawa;O.Shirota;H.Ikuta;H.Morita;K.Takeya;Y.Iitaka
  11. Chem. Pharm. Bull. v.39 no.8 Conformational Analysis of [N-Demethyl-Try($OCH_3$)-3] RA-VII, Conformationally Restricted Model Approach H.Itokawa;K.Saitou;H.Morita;K.Takeya
  12. Tetrahedron v.47 no.16;17 Conformational Analysis of Antitumor Cyclic Hexapeptides RA Series H.Morita;K.Kondo;Y.Itotsuyanagi;K.Takeya;H.Itokawa;N.Tomioka;A.Itai;Y.Iitaka
  13. Tetrahedron Lett. v.32 no.15 Eurylene, A New Squalene-Type Triterpene from Eurycoma longifolia H.Itokawa;W.Kishi;H.Morita;K.Takeya;Y.Iitaka
  14. Chem. Pharm. Bull. v.39 no.4 A Cytotoxic Substance from Sangre de Grado H.Itokawa;Y.Ichihara;M.Mochizuki;T.Enomori;H.Morita;O.Shirota;M.Inamatsu;K.Takeya
  15. Chem. Pharm. Bull. v.39 no.3 Structures and Cytotoxic Activity Relationship of Casearins, New Clerodane Diterpenes from Casearia sylvestris Sw. H.Morita;M.Nakayama;H.Kojima;K.Takeya;H.Itokawa;E.P.Schenkel;M.Motidome
  16. Chem. Pharm. Bull. v.38 no.12 New Antitumor Principle, Casearins A-F, from Casearia sylvestris Sw.(Flacourtiaceae) H.Itokawa;N.Totsuka;H.Morita;K.Takeya;Y.Iitaka;E.P.Schenkel;M.Motidome
  17. Tetrahedron Lett. v.31 no.47 New Triterpene Dimers from Maytenus ilicifolia H.Itokawa;O.Shirota;H.Morita;K.Takeya;N.Tomioka;A.Itai
  18. Shoyakugaku Zasshi v.44 no.2 A Cytotoxic Principle from Evodia rutaecarpa H.Itokawa;M.Inamatsu;K.Takeya